STAFF BOARD
Article
CHAIRMAN
Virginia Hernández Corredoira
EDITOR IN CHIEF
Manuela Velázquez Prieto
Jaime E. Poquet Jornet
MARKETING MANAGER
EDITORIAL BOARD
Ramón Jódar Masanés
Lluís Campins Bernadas
Tomás Casasín Edo
Juan Carlos Juárez Giménez
Carles Quiñones Ribas
Volume 22 - Issue 2, April-June 2020
ORIGINAL
UNIFICATION OF THE PREPARATION OF METHOTREXATE, CYTARABINE AND HYDROCORTISONE INTRATHECAL IN A SINGLE SOLUTION
LÓPEZ MONTERO ELENA, MOSQUERA TORRE ALICIA, TOURÍS LORES MANUEL, BERNÁRDEZ FERRÁN BEATRIZ, ZARRA FERRO IRENE


In our unit, the solutions of the three drugs administrated intrathecally, metho- trexate,
cytarabine and hydrocortisone, were prepared separately and differently depending on if it will be
administrated for pediatric or adult population. With the aim of unifying the preparations and
because the administration of these agents could be greatly facilitated if all three agents were
combined in a single solution, we evaluated some pharmaceutical aspects such as pH and osmolality
of com- bined preparations and the separated preparations.
It was concluded that the preparation of a single solution had better charac- teristics of
osmolality and pH for intrathecal administration than the separated preparations.

CYTARABINE – INTRAATTHHEECCCAALL – METHOTTRREEXXAATE – OSMOLALITY – PH



Fill out the form below to buy this article

Name and surname:

DNI/NIF ID/VAT IDENTIFICATION No.:

Contact Email:

Phone:

Address:

Zip code:

City:

Province:

Country:

*I have read and accept the privacy policy
Price : 30,25