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Volume 19 - Issue 6, November-December 2017
SHORT REPORTS
VANCOMYCIN-INDUCED THROMBOCYTOPENIA AND NEUTROPENIA IN NEONATE: A CASE REPORT
MARTINS PEREIRA VALE LETÍCIA, XAVIER DA COSTA TATIANA, MEIRELLY NUNES BRUNA, GOUVEIA OLIVEIRA ANTÔNIO, RANDALL MARTINS RAND


Neonates have physiological differences including a greater proportion of extravascular total body water, immature renal and hepatic function, reduced plasma protein concentrations and a relatively permeable blood brain barrier. These factors contribute to alter the pharmacokinetics parameters of drugs in neonates, increasing
the susceptibility to adverse drug events. Vancomycin-induced neonatal thrombocytopenia and neutropenia are rarely described in scientific literature. We describe a newborn who was diagnosed with early onset sepsis and vancomycin-induced thrombocytopenia and neutropenia.

NEONATE – NEUTROPENIA – THROMBOCYTOPENIA – VANCOMYCIN



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