STAFF BOARD
Article
CHAIRMAN
Manuela Velázquez Prieto
EDITOR IN CHIEF
Jaime E. Poquet Jornet
MARKETING MANAGER
Margarita Pamplona
EDITORIAL BOARD
Tomás Casasín Edo
Virginia Hernández Corredoira
Ramón Jódar Masanés
Juan Carlos Juárez Giménez
Volume 19 - Issue 4, July-August 2017
ORIGINAL
CLINICAL EXPERIENCE WITH LINEZOLID IN INTERNAL MEDICINE
MARCOS PÉREZ GEMA, CÁMARA GONZÁLEZ TIMOTEO, RECUERO GALVE LIDIA, LÁZARO MORENO TEODORO, GÓNZALEZ MORENO CARLOS, BARREDA HERNÁNDEZ DOLORES


Objective: To describe the use of linezolid in hospitalized patients in an Internal Medicine Service.

Method: Observational, descriptive and retrospective study of the use of linezolid for 12 months in an Internal Medicine Service.

Results: 88 patients were selected, with a median age of 83 years old. The most frequent indications were: skin and soft tissue infection, pneumonia and other infections. 63.6% of the treatments were initiated empirically. In 61.4% of the cases, the indication was not adjusted to the antibiotic’s indication stated on the Summary
of Product Characteristics (off-label use). Gram-positive bacteria were isolated in 62% of the cultures, all of them sensitive to vancomycin and linezolid. Only linezolid therapeutic steep-down was performed in 13.9% of the patients.

Conclusions: Linezolid is often used for unlabeled indications and fundamentally empirically. In many cases, no therapeutic steep-down of linezolid was performed after knowing the results of the microbiological cultures.

INTERNAL MEDICINE – LINEZOLID – STAPHYLOCOCCUS AUREUS – THERAPEUTIC USE



Fill out the form below to buy this article

Name and surname:

DNI/NIF ID/VAT IDENTIFICATION No.:

Contact Email:

Phone:

Address:

Zip code:

City:

Province:

Country:

*I have read and accept the privacy policy
Price : 30,25