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Volume 18 - Issue 5, September-October 2016
SHORT REPORTS
TREATMENT OF ALVEOLAR PROTE INOSIS WITH «OFF-LABEL» INHALED SARGRAMOSTIM
VÁZQUEZ BLANCO SILVIA, GARCÍA MAYO MARÍA ENCINA, VEIGA VILLAVERDE ANA BELÉN, CRESPO DIZ CARLOS


Pulmonary Alveolar Proteinosis (PAP) is a rare disease characterized by the accumulationof lipoprotein material from alveolar surfactant in the alveoli of the lungs,which consequently causes a deterioration in gas exchange. It is more prevalent in young adults, who develop gradual exertional dyspnea, hypoxemia and characteristic
radiological alterations. Bronchoalveolar Lavage (BAL) has proven to be the most effective treatment for PAP. The administration of inhaled Granulocyte Macrophage Colony Stimulating factor (GM-CS) would be an alternative therapy for this condition.

ALVEOLAR PROTEINOSIS – SARGRAMOSTIM – BRONCHOALVEOLAR LAVAGE



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